Do I need a business license to apply?

Most programs ask for proof that your business is registered. Check the eligibility section of the listing before you start.

Does GRANTSRUS decide who gets funded?

No. The organization offering the money makes the final eligibility and award decision.

Funding for small businesses

Small business grants

A small business grant is money you do not pay back, given for a specific purpose the funding organization cares about. Most programs ask what you will spend the money on, who it helps, and how you will show results.

Every listing below is a real open program. Read who can apply and the deadline first, then open the official page to apply. You always apply directly with the organization offering the money.

65 open listings in this group

Showing the 24 closing soonest. Use the search page to see the rest.

Funding opportunityGrant
NRL Long Range Broad Agency Announcement (BAA) for Basic and Applied Research
Naval Research Laboratory
Amendment 0007 The purpose of this amendment is to add Summary Topic 61-24-06 - AFFF ALTERNATIVE PROGRAM COMPATIBILITY OF FLUORINE-FREE FOAM (F3) WITH NON-ASPIRATING SPRINKLER NOZZLES to Appendix 1 in it’s entirety. All other terms and conditions remain unchanged. -------------------------------------------------------------- Amendment 0006 The purpose of this amendment is to extend the due date for acceptance of White Papers. All other terms and conditions remain unchanged. -------------------------------------------------------------- Amendment 0005 The purpose of this amendment is to provide a searchable list of Summary Topics contained in Appendix 1. Expanded descriptions of each topic can be found in the full announcement pdf. APPENDIX 1 – RESEARCH DESCRIPTION - SUMMARY TOPICS II. Detailed information about the funding opportunity The Naval Research Laboratory (NRL) is the Navy's corporate laboratory. NRL conducts basic and applied research for the Navy in a variety of scientific and technical disciplines. The basic research program is driven by perceptions about future requirements of the Navy. The Navy's operational effectiveness depends on its ability to keep pace with rapidly developing technologies. NRL contributes to this requirement by conducting research in the following areas, organized into NRL'S three research directorates and Naval Center for Space Technology: Systems Directorate Code 5000 Materials Science and Component Technology Directorate Code 6000 Ocean and Atmospheric Science and Technology Directorate Code 7000 Naval Center for Space Technology Code 8000 A. SYSTEMS DIRECTORATE - CODE 5000 53-24-01 - HIGH FREQUENCY RADAR 53-24-01C - HIGH FREQUENCY RADAR (CLASSIFIED) 53-24-02 - LOW-COST WIDEBAND ANTENNA ARRAY TECHNOLOGIES 53-24-03 - ADVANCED COMPUTATIONAL ELECTROMAGNETICS 55-24-01 - INFORMATION AND DECISION SCIENCES 55-24-02 - MATHEMATICAL FOUNDATIONS OF HIGH ASSURANCE COMPUTING 55-24-03 - HIGH ASSURANCE ENGINEERING AND COMPUTING 55-24-04 - ADVANCED NAVAL NETWORK SOLUTIONS 55-24-05 - FEDERATED, DISTRIBUTED COMPUTING/NETWORK INFRASTRUCTURE 56-24-01 - OPTICAL SCIENCES R&D 57-24-01 - ELECTROMAGNETIC TECHNIQUES AND TECHNOLOGY RESEARCH AND DEVELOPMENT 57-24-02 - SHIPBOARD ELECTRONIC WARFARE B. MATERIALS SCIENCE AND COMPONENT TECHNOLOGY DIRECTORATE CODE 6000 60-24-01 - HIGH PERFORMANCE COMPUTING ON MASSIVELY PARALLEL ARCHITECTURES 61-24-01 - ELECTROCHEMICAL ENERGY STORAGE, CONVERSION AND COMMAND/CONTROL 61-24-02 - CORROSION PROCESSES, CONTROL, MITIGATION, AND TECHNOLOGY 61-24-03 - APPLICATIONS OF MOLECULAR BIOLOGY, BIOCHEMISTRY, ANALYTICAL CHEMISTRY AND ADVANCED LASER TECHNIQUES 61-24-04 - MULTIECHELON DIAGNOSTICS (MEDx) TECHNOLOGY DEVELOPMENT AND TIERED EVALUATION 63-24-01 - MATERIALS PERFORMANCE, PROCESSING, AND MODELING 67-24-01 - BASIC AND APPLIED RESEARCH IN PLASMA SCIENCE 68-24-01 - RADIATION EFFECTS RESEARCH 68-24-02 - PHOTOVOLTAICS FOR PORTABLE POWER C. OCEAN AND ATMOSPHERIC SCIENCE AND TECHNOLOGY DIRECTORATE CODE 7000 71-24-01 - ACOUSTIC SIMULATION AND TACTICS 72-24-01 - LOW FREQUENCY RADIO INTERFEROMETRY 72-24-02 - OPTICAL REMOTE SENSING OF THE COASTAL REGIME 72-24-03 - REMOTE SENSORS AND IMAGING SYSTEMS 72-24-04 - AIRBORNE, SHIPBOARD, AND OVERHEAD DATA ACQUISITION AND ANALYSIS 73-24-01 - OCEAN DYNAMICS AND PREDICTION OCEANOGRAPHY 73-24-02 - SEAFLOOR SCIENCES 73-24-03 - GEOSPATIAL SCIENCES AND TECHNOLOGY 75-24-01 - ATMOSPHERIC EFFECTS, ANALYSIS, AND PREDICTION 76-24-01 - RESEARCH INTO SPACE, BACKGROUNDS, IMAGING AND MODELING D. NAVAL CENTER FOR SPACE TECHNOLOGY CODE 8000 82-24-01 - SPACECRAFT & SPACE SYSTEMS TECHNOLOGY -------------------------------------------------------------- Amendment 0004 The purpose of this amendment is to extend the due date for acceptance of White Papers and revise Appendix 1 Summary Topics and email addresses in it’s entirety. -------------------------------------------------------------- Amendment 0003 The purpose of this amendment is to extend the due date for acceptance of White Papers. All other terms and conditions remain unchanged. ------------------------------------------------------------- Amendment 0002 The purpose of this amendment is to extend the due date for acceptance of White Papers. All other terms and conditions remain unchanged. ------------------------------------------------------------- Amendment 0001 The purpose of this amendment is to extend the due date for acceptance of White Papers. All other terms and conditions remain unchanged. -------------------------------------------------------------- The Naval Research Laboratory is interested in receiving innovative proposals that offer potential for advancement and improvement in the technical topic areas listed. This notice constitutes a Broad Agency Announcement (BAA) as contemplated in FAR 6.302(d) that provides for the competitive selection of research proposals. The Government reserves the right to select for award all, some, or none of the proposals received. Awards under this BAA are expected to take the form of Contracts, Grants, Cooperative Agreements and Other Transactions may also be awarded if appropriate. NRL encourages Educational Institutions, Small Businesses (SBs), Small Disadvantaged Business Concerns (SDBs) and Historically Black Colleges and Universities (HBCUs) and Minority Institutions (MIs) to submit proposals under this BAA. In order to conserve valuable offeror and Government resources, prospective offerors shall first submit a White Paper (WP) to the email address identified in the individual Summary Topics contained in Appendix 1, to include a rough cost estimate. If there is interest in the proposed research the offeror will be invited to submit a Formal Proposal. The selection of proposals for award will be based on a scientific review of proposals submitted in response to each BAA Summary Topic. The major purpose of the evaluation will be to determine the relative merit of the technical approach of each proposal. Business and contractual aspects, including proposed cost and cost realism, will also be considered as part of the evaluation. Selection of proposals for award will be based on the potential benefits to the Government weighed against the cost of the proposals, in view of the availability of funds. The complete BAA including proposal preparation instructions, award considerations, and evaluation criteria is also available at https://www.nrl.navy.mil/Doing-Business/Contracts/Broad-Agency-Announcements/ .
Amount:
$0
Closes:
Sep 30, 2026
Funding opportunityGrant
FY25 Long Range Broad Agency Announcement (BAA) for Navy and Marine Corps Science and Technology
Office of Naval Research
ONR, ONRG, and MCWL are interested in receiving proposals for Long-Range S&T Projects that offer potential for advancement and improvement of Navy and Marine Corps operations. Readers should note that this is an announcement to declare ONR, ONRG and MCWL’s broad role in competitive funding of meritorious research across a spectrum of science and engineering disciplines. All responsible sources from academia, industry and the research community worldwide may submit proposals under this BAA. All businesses, both small and large, are encouraged to submit proposals and compete for funding consideration.
Closes:
Sep 30, 2026
Funding opportunityGrant
Advanced Technological Education
U.S. National Science Foundation
With a focus on two-year Institutions of Higher Education (IHEs), the Advanced Technological Education (ATE) program supports the education of technicians for the high-technology fields that drive our nation's economy. The program involves partnerships between academic institutions (grades 7-12, IHEs), industry, and economic development agencies to promote improvement in the education of science and engineering technicians. It is strongly recommended that projects be faculty-led and required that courses and programs are credit-bearing, although materials developed may also be used for incumbent worker education. Materials may also be adapted and implemented as credit-bearing courses. The ATE program supports curriculum development; professional development of college faculty and secondary school teachers; career pathway development for both students and incumbent workers; and other activities including applied research projects that advance the knowledge base related to technician education. The ATE program encourages partnerships with other entities that may impact technician education. For example, with the National Institute of Standards and Technology (NIST) Manufacturing Extension Partnerships (MEPs) ( http://www.nist.gov/mep/index.cfm ) as applicable to support technician education programs and the industries they serve; and Manufacturing USA Institutes( https://manufacturing.gov/ ) addressing workforce development issues. The ATE program encourages proposals from Minority Serving Institutions as well as other institutions that support the recruitment, retention, and completion (certificate, degree, program)of the full spectrum of diverse talent that society has to offer, which includes underrepresented and underserved communities, in STEM technician education programs that award associate degrees.
Amount:
$475,000 to $7,500,000
Closes:
Oct 1, 2026
Funding opportunityGrant
Engineering Research Initiation (ERI)
U.S. National Science Foundation
The NSF Directorate for Engineering (ENG) seeks to build engineering research capacity across the nation by investing in new academic investigators who have yet to receive sufficient research funding from Federal Agencies. The Engineering Research Initiation (ERI) program will support new investigators as they initiate their research programs and advance in their careers as researchers, educators, and innovators. This funding opportunity aims to broaden the base of investigators involved in engineering research and therefore is limited to investigators that are not affiliated with “very high research activity” R1 institutions (according to the Carnegie Classification https://carnegieclassifications.iu.edu/ ).
Amount:
$200,000
Closes:
Oct 9, 2026
Funding opportunityGrant
NSF Small Business Innovation Research / Small Business Technology Transfer Phase I, Phase II, Fast-Track Programs: A Pilot Emphasis on Scientific Instrumentation
U.S. National Science Foundation
NSF invests in scientific discoveries, technological breakthroughs, and transformative innovations that strengthen economic growth, enhance security, and improve the lives of Americans and people around the world. Our ability to support that mission requires a robust scientific and engineering (S&E) enterprise in the United States that allows scientists to innovate at the frontier. In addition to funding scientists, America needs next-generation scientific instrumentation that allows scientists to pursue new innovations. In many fields, it is critical that this new scientific instrumentation is developed in the United States. In support of this mission, NSF is initiating a pilot emphasis area for its SBIR/STTR programs to invest in startups and small businesses that are specifically developing enabling technologies that include next-generation instrumentation, novel experimental platforms, and other scientific equipment to advance the frontiers of scientific discovery and strengthen the American scientific and engineering enterprise. This encompasses novel instrumentation necessary for the coming era of AI-driven discoveries. This pilot will prioritize investing in the necessary infrastructure to support entirely new fields of scientific discovery, making new technological breakthroughs and transformative applications possible. Through this approach, NSF will continue to lead in propelling the scientific enterprise to new frontiers. This pilot emphasis area for the NSF SBIR/STTR programs funds across enabling technology areas and market sectors in alignment with the above goals; the programs do not solicit specific technologies for the purpose of procuring goods and services for the agency from startups and small businesses. NSF will continue to invest in other deep-tech ventures through the historic NSF SBIR/STTR programs available here. Funding opportunities are available through the NSF SBIR/STTR programs: Phase I, Phase II, Fast-Track, and Supplements. Each company can receive up to $2.0 million for R&D. Separately, NSF welcomes Strategic Breakthrough proposals, upon recommendation from the Program Officer, for Phase II awardees. NSF takes no equity and awardees keep full ownership of their company and intellectual property. Expanding Participation in STEM and Gold Standard Science: NSF prioritizes cutting-edge discovery science and engineering research, advancing technology and innovation, and creating opportunities for all Americans. NSF also expects the highest standards of scientific rigor, integrity and adherence to tenets of Gold Standard Science in proposals, as appropriate for the field of science and research modality.
Closes:
Nov 4, 2026
Funding opportunityGrant
Unlocking Dataset Value for AI-Enabled Scientific Discovery (AI Datasets)
U.S. National Science Foundation
This program will advance scientific community datasets to enable scientific discovery and innovation using artificial intelligence (AI) and other methods. Its goal is to increase the value that can be derived from existing scientific datasets by leveraging novel methods and artificial intelligence (AI). This will unlock new AI-driven insights. It can enable interdisciplinary research. It also enables investigations outside of the original motivation for data collection and analysis. The program seeks to 1) apply AI-based capabilities to feature extraction and metadata generation, and the integration of multiple datasets. 2) Develop robust data pipelines necessary for automated analysis of existing datasets and similar use-cases by AI tools and systems. 3) Augment and/or harmonize existing datasets to better enable use by AI data pipelines and automated analysis. Proposals should address dataset security and integrity. Governance and the process for scientific communities to contribute to the datasets should also be addressed. Proposals are encouraged to leverage existing resources. These may include NSF data platforms , the NSF Integrated Data Systems and Services program , the NSF-led National AI Research Resource , the Genesis Mission platform , or other national infrastructure. NSF is open to exploring partnerships with philanthropy, private industry, or the non-profit sector to support additional proposals or collaborative opportunities that will advance AI-driven scientific discovery through unlocking the value of high-impact scientific datasets. Expanding Participation in STEM, NSF Priorities, and Gold Standard Science: NSF prioritizes cutting-edge discovery science and engineering research, advancing technology and innovation, and creating opportunities for all Americans. NSF has established priorities set forth by Congress, the administration and the NSF director to promote NSF's mission . Proposers should review the list of NSF priorities and are encouraged to align their proposals with them, where appropriate. NSF also expects the highest standards of scientific rigor, integrity and adherence tenets of Gold Standard Science in proposals, as appropriate for the field of science and research modality.
Closes:
Nov 4, 2026
Funding opportunityGrant
Amyotrophic Lateral Sclerosis (ALS) Intermediate Patient Population Expanded Access (U01 Clinical Trial Required)
National Institutes of Health
The purpose of this Notice of Funding Opportunity (NOFO) is to solicit applications for the conduct of scientific research utilizing data from expanded access (EA) for investigational drugs or biological products as described in section 561 of the Federal Food, Drug, and Cosmetic Act (21 U.S.C. 360bbb). These applications will target intermediate size populations of patients living with amyotrophic lateral sclerosis (ALS) who are not eligible for ongoing clinical trials for the prevention, diagnosis, mitigation, treatment, or cure of ALS.
Closes:
Nov 10, 2026
Funding opportunityGrant
Special Program Announcement for Office of Naval Research Research Opportunity: FY27 Communications and Networking Applied Research
Office of Naval Research
The proposed topic will develop and mature Communications and Networking technologies for Naval operations. Background: A Design for Maritime Superiority (2018) describes an operational architecture for distributed maritime operations (DMO) that "... will provide accurate, timely, and analyzed information to units, warfighting groups, and fleets." A critical component of this architecture is the Naval Tactical Grid (NTG) to connect distributed units into groups and distributed groups into fleets. Communications and networking technologies that can provide seamless, robust, connectivity are key enablers for the NTG. These technologies will be deployed on a variety of platforms, both manned and unmanned, operating under challenging environmental and operational warfare conditions (lack of infrastructure, mobility, spectrum limitations, interference, multipath, atmospherics, jamming, electronic intercept, size/weight/power constraint, etc.) in different domains (land, maritime [includes both surface and undersea], cyber, and space). Successful Command and Control (C2) and decision making, at all levels of command, for DMO is critically dependent on these communications and networking technologies
Amount:
$250,000 to $500,000
Closes:
Nov 16, 2026
Funding opportunityGrant
National Science Foundation Translation to Practice
U.S. National Science Foundation
The U.S. NSF Directorate for Technology, Innovation and Partnerships (NSF TIP) partners across sectors to advance three primary focus areas – accelerating technology translation and development, fostering regional innovation and economic growth, and preparing the American workforce for future high-wage jobs in STEM fields. The translation of research to practice ensures that the insights and innovations developed through scientific study and experimentation have tangible, positive impacts for the Nation. These impacts include improving the quality of life, promoting economic and job growth, ensuring national security, and maintaining global competitiveness. Indeed, scientific and engineering breakthroughs have the potential to address critical societal challenges in industries such as aerospace, agriculture, communications, education, energy, healthcare, national security, and transportation – but the translation of discoveries and innovations from the laboratory to society often takes many forms including non-linear pathways. The NSF TTP program was developed with several goals in mind: To identify and support use-inspired research and translational activities enabling a continuum from foundational research to practice; To develop partnerships and collaborations between institutions of higher education and other entities (e.g., industry, state/local/national government agencies, philanthropies, open-source ecosystems, for-benefit, for-profit and non-profit organizations, international organizations, etc.); To promote and advance the education and training of students and postdoctoral researchers, encouraging the participation of all Americans in STEM including innovation and entrepreneurship; and To identify future customer needs and opportunities and bring these to the forefront in the conduct of use-inspired research and translational activities. The NSF TTP program offers three tracks that represent different starting points or stages in moving discoveries and innovations from the laboratory to practice: NSF TTP-Explore (NSF TTP-E) is a pilot track that is likely to be the first step for researchers seeking to translate their basic research to practice. To be eligible for the NSF TTP-E track, proposers must have an active, eligible, NSF research award (see Eligibility Information for further details). TTP-E is designed to encourage current, eligible NSF awardees to intentionally pursue applications of their research with the potential for societal impact. The NSF TTP-E track provides the opportunity to obtain an extension of the initial award period of a current NSF award for up to two years in order to offer investigators an opportunity to explore adventurous, high-risk, use-inspired research and initial translational activities as the starting point for translation that was not covered by the original research award. NSF TTP-Translate (NSF TTP-T) starts with use-inspired research and initial translational activities and further matures the idea(s), iterates and improves the solution(s), and lowers the barrier(s) to effective translation of research from lab to practice. NSF TTP-Partner (NSF TTP-P) supports translational efforts that demand one or more partnerships for technology development and deployment. Here, strategic partnerships with stakeholders beyond U.S. institutions of higher education are essential ingredients for success and may include industry partners, government entities at all levels, philanthropies, international organizations, or other groups associated with large scale productization and distribution. The NSF TTP-P track requires an NSF-Catalyzed Partnership with an organization that will assist in the translation to practice. In addition to the Principal Investigator (PI), NSF TTP-P proposals must include a co-PI or Senior/Key Personnel who is a member or employee of the NSF-Catalyzed Partner. Partnerships with U.S. institutions of higher education are valued, but NSF TTP strongly prioritizes NSF-Catalyzed Partnerships that are able to help bring the product, process, or service to the market, potentially through licensing agreements, startup or small business formation, incorporation into an existing open-source ecosystem, development into standards setting arrangements, etc.
Amount:
$600,000 to $2,000,000
Closes:
Nov 17, 2026
Funding opportunityGrant
Arctic Research Opportunities
U.S. National Science Foundation
The National Science Foundation (NSF) invites investigators at U.S. organizations to submit proposals to the Arctic Sciences Section in the Office of Polar Programs (OPP) within the Geosciences Directorate, to conduct research about the Arctic region. The goal of this solicitation is to attract research proposals that advance a fundamental, process, and/or systems-level understanding of the Arctic's rapidly changing natural environment, social and cultural systems, and, where appropriate, to improve our capacity to project future change. The Arctic Sciences Section supports research focused on the Arctic region and its connectivity with lower latitudes. The scientific scope is aligned with, but not limited to, research priorities outlined in the Interagency Arctic Research Policy Committee (IARPC) five-year plan. The Arctic Sciences Section coordinates with programs across NSF and with other federal and international partners to co-review and co-fund Arctic-related proposals as appropriate. The Arctic Sciences Section also maintains Arctic logistical infrastructure and field support capabilities that are available to enable research.
Amount:
$330,000
Closes:
Jan 15, 2027
Funding opportunityGrant
Mid-scale Research Infrastructure-1
U.S. National Science Foundation
NSF-supported science and engineering research increasingly relies on cutting-edge infrastructure. With its Major Research Instrumentation (MRI) program and Major Multi-user Facilities ("Major Facilities") projects, NSF supports infrastructure projects at the lower and higher range of infrastructure project costs, Foundation-wide, across science and engineering research disciplines. The Foundation-wide Mid-scale Research Infrastructure opportunity is intended to provide NSF with an agile, Foundation-wide process to fund experimental research capabilities in the mid-scale range between MRI and Major Multi-user Facilities. NSF defines Research Infrastructure (RI) as any combination of facilities, equipment, instrumentation, or computational hardware or software, and the necessary human capital in support of the same. Major facilities and mid-scale projects are subsets of research infrastructure. The NSF Mid-scale Research Infrastructure-1 Program (Mid-scale RI-1) supports either design activities or implementation of unique and compelling RI projects. Mid-scale implementation projects may include any combination of equipment, instrumentation, cyberinfrastructure, broadly used large scale datasets and the personnel needed to successfully commission the project. Mid-scale RI-1 design activities include the design efforts intended to lead to eventual implementation of a mid-scale class RI project. Mid-scale RI-1 projects should involve the training of a diverse workforce engaged in the design and implementation of STEM research infrastructure. Mid-scale RI-1 projects should directly enable advances in any of the research domains supported by NSF. Projects may also include upgrades to existing research infrastructure. Mid-scale RI-1 emphasizes strong scientific merit, a response to an identified need of the research community and/or fulfillment of a national need to enable U.S. researchers to be competitive in a global research environment. Well-conceived technical and management plans are essential for both design and implementation proposals, as are well-developed plans (e.g., mentoring and professional development) for student training and the involvement of a diverse STEM workforce in all aspects of mid-scale design and/or implementation activities. The inclusion of individual project participants that will lead to a supportive working environment is especially encouraged at all levels of the project team. Within Mid-scale RI-1, proposers may submit two types of projects, “Implementation” (e.g., acquisition and/or construction) or “Design”. The “Design” track is intended to facilitate progress toward readiness for a mid-scale range implementation project. Both Implementation projects and Design activities may involve new or upgraded research infrastructure. Mid-scale RI-1 "Implementation" projects may have a total project cost ranging from $4 million up to but not including $20 million. Mid-scale RI-1 "Design" activities may request less than $4 million, with a minimum request of $400,000 and a maximum request up to but not including $20 million, as appropriate, to prepare for a future mid-scale range implementation project. Note: Successful award of a Mid-scale RI-1 design activity does not imply NSF's commitment to the future implementation of the project being designed, nor is a Mid-scale RI-1 design award required for the submission of an implementation project. The Mid-scale RI-1 Program seeks to broaden the representation of PIs and institutions in its award portfolio, including a geographically diverse set of institutions (especially those in EPSCoR jurisdictions). Proposals submitted by, or involving partnerships between institutions are encouraged. Participation in this opportunity is encouraged for the full spectrum of diverse talent society has to offer to include PIs who are women, early-career researchers, persons with disabilities, or members of other groups underrepresented in STEM. To improve participation in science and engineering research for persons with disabilities, Mid-scale RI-1 encourages PIs to incorporate accessibility as part of Mid-scale RI-1 design activity and implementation projects. Please consult NSF's Research Infrastructure Guide, or RIG (available at https://www.nsf.gov/bfa/lfo/lfo_documents.jsp ), for definitions of certain terms used in this solicitation, such as the Project Execution Plan (PEP) and Design and Execution Plan (DEP). The RIG provides guidance specific to Mid-scale Research Infrastructure Projects, including references to other parts of the RIG as needed. Note that PEP or DEP should be appropriately scaled for the complexity of the project and may not require all of the elements described in the RIG. Mid-scale research infrastructure projects with total project costs beyond the Mid-scale RI-1 Program limit are separately solicited through the Mid-scale RI-2 Program. Proposals to the Mid-scale RI-1 Program with total project costs outside of this solicitation's budgetary limits, either during initial submission or after cost analyses/revisions during subsequent review, are subject to return without further review.
Amount:
$4,000,000 to $19,999,999
Closes:
Feb 8, 2027
Funding opportunityGrant
Pathways to Enable Secure Open-Source Ecosystems (PESOSE)
U.S. National Science Foundation
The Pathways to Enable Secure Open-Source Ecosystems (PESOSE) program supports the translation of open-source science and engineering-focused research products into safe and sustainable ecosystems that address national and societal challenges. Open-source tools such as software, hardware, machine learning models, languages, and data platforms are designed to be shared as they are publicly-accessible and modifiable. These tools spark innovation in critical fields as varied as artificial intelligence (AI) and cloud computing, banking, healthcare, research, education, next-gen manufacturing, mobility, and National security (including cybersecurity). PESOSE supports the creation of managing organizations for these ecosystems, ensuring strong governance, distributed development, and broad user communities across academia, industry, and government. PESOSE also supports enhancements to the safety, security, and privacy of Open-Source Ecosystems (OSE) by addressing significant vulnerabilities, both technical and socio-technical, to improve the resistance of the ecosystem against threats. This solicitation seeks three types of proposals, allowing teams to propose specific activities to: 1) scope and plan the establishment of an OSE, 2) establish and expand a sustainable OSE based on a robust, promising open-source product that meets an emergent societal or national need, and 3) improve the safety, security, and privacy of an existing OSE and its products.
Closes:
Mar 2, 2027
Funding opportunityGrant
Coupling, Energetics, and Dynamics of Atmospheric Regions
U.S. National Science Foundation
The Coupling, Energetics, and Dynamics of Atmospheric Regions (CEDAR) program supports research to increase our understanding of the behavior of atmospheric regions from the middle atmosphere upward through the thermosphere and ionosphere into the exosphere. Projects explore coupling, energetics, chemistry, and dynamics on regional and global scales. The research topics include investigations of upper atmosphere responses due to a) processes driven by the lower atmospheric perturbations and (b) solar radiation and particle inputs from above. The activities supported by this program include observations from ground-based and space-based platforms, as well as theory and modeling of the upper atmosphere of the Earth and other planets in our solar systems. Novel approaches that include AI and ML tools and open data and open science practices are encouraged.
Amount:
$100,000 to $750,000
Closes:
Mar 3, 2027
Funding opportunityGrant
UNITED STATES MILITARY ACADEMY Broad Agency Announcement
Dept of the Army -- Materiel Command
The U.S. Military Academy at West Point's mission is "to educate, train, and inspire the Corps of Cadets so that each graduate is a commissioned leader of character committed to the values of Duty, Honor, Country and prepared for a career of professional excellence and service to the Nation as an officer in the United States Army." The United States Military Academy is located at West Point, New York. USMA executes research to enhance the education of cadets, develop the faculty professionally, and address important issues facing the Army and the Nation. In addition, the Academy conducts research and analysis in emerging fields that may realize novel or vastly improved Army capabilities. At West Point, research is organized and administered through centers and institutes, most of which reside within academic departments. These centers and institutes, affiliated with each other through the Academy Research Council (ARC), coordinated and supported by the Academic Research Division (ARD), provide the infrastructure necessary to tackle the nation’s and the world’s most challenging problems. Our research centers and institutes bring context to the classroom, are central to our vibrant and pioneering faculty, and are one way West Point connects to the Army and to the Nation. Our students are driven, our faculty is world-class, and through our centers, scholars and scientists thrive and produce their best work. Cadets regularly win Best Paper Awards at national and international graduate-level conferences, our faculty hold fellowships and chairmanships in their discipline's national organizations and our products are deployed to the soldier. In addition to applied research, there are centers and institutes at West Point that focus on other aspects of the USMA mission. The USMA BAA identifies topics of interest to the USMA departments, directorates, and research centers and institutes. These groups focus on executing in-house research programs, with a significant emphasis on collaborative research with other organizations. The groups fund a modest amount of extramural research in certain specific areas, and those areas are described in this BAA. The USMA BAA seeks proposals from institutions of higher education, nonprofit organizations, state and local governments, foreign organizations, foreign public entities, and for-profit organizations (i.e., large and small businesses) for research based on the following campaigns: Socio-Cultural; Information Technology; Ballistics, Weapons, and Protections; Energy and Sustainability; Materials, Measurements, and Facilities; Unmanned Systems and Space; Human Support Systems; and Artificial Intelligence, Machine Learning, and Quantum Technologies. Proposals are sought for cutting-edge innovative research that could produce discoveries with a significant impact to enable new and improved Army technologies and related operational capabilities and related technologies. The specific research areas and topics of interest described in this document should be viewed as suggestive, rather than limiting.
Closes:
Mar 31, 2027
Funding opportunityGrant
NARMS Cooperative Agreement Program to Strengthen Antibiotic Resistance Surveillance in Retail Food Specimens
Food and Drug Administration
This Funding Opportunity Announcement (FOA) issued by the Food and Drug Administration (FDA), Center for Veterinary Medicine (CVM), builds upon the National Antimicrobial Resistance Monitoring System (NARMS) which was initiated in 1996 as one of the key activities in a national action plan to combat antibiotic resistance threats. The purpose of this FOA is to protect and promote public health by enhancing, strengthening, and sustaining antibiotic resistance surveillance in retail food specimens within the NARMS program. The NARMS cooperative agreement is intended to improve the detection of antibiotic resistance among bacteria in food commodities, as well as expand to new sites to expand the scope of sampling. Measurable outcomes of the program will be in alignment with the NARMS Objectives.
Amount:
$0 to $200,000
Closes:
Apr 1, 2027
Funding opportunityGrant
NIH, CDC and FDA Small Business Innovation Research Grant (Parent SBIR [R43/R44] Clinical Trial Optional)
National Institutes of Health
The Small Business Innovation Research (SBIR) program helps United States small business concerns (SBCs) bring scientific innovations to the marketplace. The SBIR program supports feasibility studies to later research and development (R&D) needed to develop a commercial product.
Closes:
Apr 5, 2027
Funding opportunityGrant
NIH Small Business Technology Transfer Grant (Parent STTR [R41/R42] Clinical Trial Optional)
National Institutes of Health
The Small Business Technology Transfer (STTR) grant program helps United States small business concerns (SBCs) that partner with a nonprofit research institution bring scientific innovations to the marketplace. The STTR program supports feasibility studies to later stage research and development (R&D) needed to develop a commercial product.
Closes:
Apr 5, 2027
Funding opportunityGrant
DEVCOM ARMY RESEARCH LABORATORY BROAD AGENCY ANNOUNCEMENT FOR FOUNDATIONAL RESEARCH
Dept of the Army -- Materiel Command
The purpose of this combined Broad Agency Announcement (BAA) under Federal Acquisition Regulation (FAR) Part 35 and Funding Opportunity Announcement (FOA) under 2 Code of Federal Regulations (CFR) 200.204 (henceforth referred to as “BAA”) is to solicit research proposals for submission to the U.S. Army Combat Capabilities Development Command (DEVCOM) Army Research Laboratory (ARL) for funding consideration. Prior to this announcement, ARL announced two separate BAAs to support the mission: 1) W911NF-17-S-0002 titled “Army Research Laboratory Army Research Office Broad Agency Announcement for Fundamental Research”; and 2) W911NF-17-S-0003 titled “Army Research Laboratory Broad Agency Announcement for Basic and Applied Scientific Research”. This announcement succeeds BAA W911NF-17-S-0002 and BAA W911NF-17-S-0003 combining the opportunities into a single announcement. ARL’s mission as the Army’s foundational research laboratory is to Operationalize Science to ensure overmatch in any future conflict. ARL’s foundational research mission spans basic research (budget activity 6.1) and applied research (budget activity 6.2) as defined by 32 CFR 22.105 but may include advanced technology development (budget activity 6.3) and advanced component development and prototypes (budget activity 6.4) when opportunities arise to directly or indirectly help achieve ARL’s mission. ARL partners across the national security enterprise to deliver fundamentally advantageous change that is rooted in the creation and exploitation of scientific knowledge. This publication constitutes a BAA for awards as contemplated in FAR 6.102(d)(2) and 35.016 as well as a merit-based, competitive procedure in accordance with the Department of Defense Grant and Agreement Regulations (DoDGARS) at 32 CFR 22.315(a) and the Office of the Under Secretary of Defense for Acquisition and Sustainment Other Transaction Guide version 2.0 dated July 2023. This BAA document, and the online list of research topics found on the ARL BAA topics website at https://www.arl.devcom.army.mil/opportunities/arl-baa/ , sets forth ARL’s research topics of interest for whitepapers and proposals. This BAA is issued under FAR 6.102(d)(2), which provides for the competitive selection of basic and applied research proposals, and 10 U.S.C. 4001, 10 U.S.C. 4021, and 10 U.S.C. 4022, which provide the authorities for issuing awards under this announcement for basic and applied research. The definitions of basic and applied research may be found at 32 CFR 22.105. Proposals submitted in response to this BAA and selected for award are considered to be the result of full and open competition and in full compliance with the provision of Public Law 98-369, “The Competition in Contracting Act of 1984” and subsequent amendments.
Closes:
Nov 20, 2027
Funding opportunityGrant
DEVCOM ANALYSIS CENTER BROAD AGENCY ANNOUNCEMENT FOR APPLIED RESEARCH
Dept of the Army -- Materiel Command
The purpose of this Broad Agency Announcement (BAA) under Federal Acquisition Regulation (FAR) Part 35 and Funding Opportunity Announcement (FOA) under 2 Code of Federal Regulations (CFR) 200.204 (henceforth referred to as “BAA”) is to solicit research proposals for submission to the U.S. Army Combat Capabilities Development Command (DEVCOM) Analysis Center (DAC) for funding consideration. The DAC is the Army's foundation for data-driven analytical decisions across the lifecycle to ensure overmatch for a lethal Army. DAC’s mission is to: Inform Army modernization and readiness decisions with objective Analysis enabled through Tool development and Data curation. DAC partners across the national security enterprise to deliver fundamentally advantageous change that is rooted in the creation and exploitation of scientific knowledge. DAC accomplishes this mission by funding the areas of applied research (budget activity 6.2), as defined by 32 CFR 22.105, advanced technology development (budget activity 6.3), and advanced component development and prototypes (budget activity 6.4). Whitepapers for initial concept reviews and full proposals are sought from institutions of higher education, nonprofit organizations, state and local governments, foreign organizations, foreign public entities, and for-profit organizations (i.e. large and small businesses) for scientific research that supports the DAC mission. The DAC BAA generally conforms to the portfolio structured around research area based mission execution. Whitepapers and full proposals are expected to be for cutting-edge innovative research that could produce discoveries with a significant impact to enable new and improved Army technologies and related operational capabilities and related technologies. In an effort to provide DAC's research topics and related information in an easy to digest format, DAC has published the following public website listing all current DAC research topics: https://www.army.mil/article/261533 , hereafter referenced as the DAC BAA topics website. DAC focuses on executing in-house research programs but supplements our efforts with support from the broader technology base and Academia. DAC funds a modest amount of extramural research in certain specific areas, and those areas are described on the DAC BAA topics website. Changes to these topics will be made using this website on an as needed basis. A change to the DAC BAA topics website is not an amendment to this BAA and will not be posted on https://www.grants.gov/ and https://sam.gov/ . A change to this document, the BAA itself, is an amendment and will be posted on https://www.grants.gov/ and https://sam.gov/ . DAC will maintain a daily static snapshot of the DAC BAA topics website to ensure submissions are aligned with listed research topics on the day of submission. Interested parties are encouraged to continually browse the DAC BAA topics website for white paper and proposal topics that DAC desires to explore. These specific research topics should be viewed as suggestive, rather than limiting. DAC is always interested in considering other innovative research concepts of relevance to the Army if those concepts align with DAC's mission. Please see Section II, Detailed Information about the Funding Opportunity, for more information on the DAC research topics advertised through this BAA. Interested parties should also review https://www.grants.gov/ and https://sam.gov/ to obtain the latest version of the BAA for whitepaper and proposal submission requirements.
Closes:
Jan 4, 2028
Funding opportunityGrant
Reissue of RFA-FD-22-001 - Efficient and Innovative Natural History Studies Addressing Unmet Needs in Rare Diseases (R01 Clinical Trials Optional)
Food and Drug Administration
The purpose of this notice of funding opportunity (NOFO) is to support efficient and innovative natural history studies that advance medical product development in rare diseases/conditions with unmet needs. Through the support of natural history studies with high quality and interpretable data elements, FDA expects to address critical knowledge gaps, remove major barriers to progress in the field, exert a significant and broad impact on a specific rare disease or multiple rare diseases with similar pathophysiology, and facilitate rare disease product development.
Amount:
$0 to $600,000
Closes:
Feb 8, 2028
Funding opportunityGrant
Reissue of RFA-FD-23-001- Clinical Studies of Orphan Products Addressing Unmet Needs of Rare Diseases (R01 Clinical Trials Required)
Food and Drug Administration
The purpose of this Notice of Funding Opportunity (NOFO) is to fund clinical trials of products evaluating efficacy and/or safety in support of a new indication or change in labeling to address unmet needs in rare diseases or conditions. Additionally, through the funding of collaborative, efficient, and/or innovative clinical trials, FDA expects to increase the number of approved treatments for rare diseases and exert a broad and positive impact on rare disease drug development.
Amount:
$0 to $900,000
Closes:
May 16, 2028
Funding opportunityGrant
F24AS00298 Cooperative Agriculture
Fish and Wildlife Service
The objectives for the use of cooperative agriculture in the National Wildlife Refuge System (NWRS) are: production or modification of specific cover types or growing methods that meet the life history requirements of species for which we have established objectives (e.g., waterfowl production); production of foods for wildlife species for which we have established objectives; and/or maintenance, rehabilitation, or reestablishment of natural habitat. Cooperative agriculture is when a person or entity conducts agricultural practices on NWRS lands in support of the Service’s conservation and resource management objectives and there is substantial involvement between the Service and that person or entity. The NWRS uses cooperative agreements, known as Cooperative Agriculture Agreements (CAAs), as the legal instruments to formalize the agreement between the Service and the program participant. The cost-sharing of a person or entity in cooperative agricultural on NWRS lands can vary depending on the needs and objectives of the particular NWRS land. For example, the Service may provide the cooperator with the right to perform agricultural practices on NWRS land and a percentage of any resulting crop yield, as well as the ability to use Service water, equipment, and/or refuge staff. In exchange, the cooperator may provide the Service with labor, equipment, and materials; a percentage of any resulting crop yield; and/or maintenance, rehabilitation, or reestablishment of specific habitat conditions on NWRS lands. In addition to or instead of cost-sharing, the Service may accept bids for payment for the person or entity’s agriculture use (e.g. haying or grazing) on NWRS lands in compliance with the Refuge Revenue Sharing Act. This is a nonfinancial assistance program. No Federal funds are obligated or awarded to program participants. Because a CAA is not a financial assistance award, it is not subject to the regulations at 2 CFR 200 or policy in parts 515 and 516 of the Fish and Wildlife Service Manual.
Amount:
$0
Closes:
Mar 7, 2029
Funding opportunityGrant
ARMY APPLICATIONS LAB BROAD AGENCY ANNOUNCEMENT FOR DISRUPTIVE APPLICATIONS
Dept of the Army -- Materiel Command
This BAA sets forth research areas of interest to the Army Applications Lab (AAL). This BAA is issued under paragraph 6.102(d)(2) of the Federal Acquisition Regulation (FAR), which provides for the competitive selection of basic and applied research proposals, and 10 U.S.C. 2358, 10 U.S.C. 2371, and 10 U.S.C. 2371b, which provide the authorities for issuing awards under this announcement for basic and applied research. The definitions of basic and applied research may be found at 32 Code of Federal Regulations (CFR) 22.105. The definitions of basic and applied research may be found at 32 Code of Federal Regulations (CFR) 22.105. Proposals submitted in response to this BAA and selected for award are considered to be the result of full and open competition and in full compliance with the provision of Public Law 98- 369, "The Competition in Contracting Act of 1984" and subsequent amendments.
Closes:
Apr 4, 2029
Funding opportunityGrant
NIH Small Business Innovation Research (SBIR) Phase IIB Strategic Breakthrough Award (Parent [R44] Clinical Trial Optional)
National Institutes of Health
The NIH Phase IIB Strategic Breakthrough award bridges the funding gap between the end of a Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) Phase II award and commercialization. The Phase IIB Strategic Breakthrough provides previously funded NIH SBIR or STTR projects additional support for later-stage research and development (R&D).
Closes:
Apr 5, 2029

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